在聚合的多细胞性中,积极分类的进化有多种途径
Kayla S Stoy1,2,3, Kathryn A MacGillivray1,3, Anthony J Burnetti1
1School of Biological Sciences, Georgia Institute of Technology. Atlanta, USA.
bioRxiv : the preprint server for biology
|March 3, 2025
概括
多细胞性需要选择才能转向集体. 在酵母菌中,遗传分类是间接进化的,而不是通过多细胞特征的直接选择,突出了聚合多细胞进化的约束.
科学领域:
- 进化生物学是进化的生物学.
- 微生物学 微生物学
背景情况:
- 过渡到多细胞性包括将选择从细胞转移到集体.
- 聚合性生物体在适应多细胞特征方面面临挑战,因为需要基因分类.
研究的目的:
- 通过实验进化来研究基因组合在多细胞适应中的演化和作用.
- 了解酵母花中遗传分类的机制和适应意义.
主要方法:
- 在快速定位的选择下,花化的*Saccharomyces cerevisiae*的实验进化.
- 基因重建实验和蛋白质结构建模,以确定分类的途径.
主要成果:
- 在19个酵母系中的13个在840代后进化了增加的积极遗传分类.
- 分类并没有为结算提供竞争优势,这表明间接演变.
- 确定了两条导致分类的途径: *FLO1* 基因突变和增强的整体粘附.
结论:
- 遗传分类可以通过细胞水平特征的选择间接进化,不一定是通过集体特征的直接选择.
- 细胞水平的适应可以在多细胞适应之前进行并使其成为可能.
- 聚合多细胞性的基本约束可能解释了这种血统的简单性.
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