相关实验视频

Updated: May 24, 2025

Identification of Cyclin-dependent Kinase 1 Specific Phosphorylation Sites by an In Vitro Kinase Assay
12:26

Identification of Cyclin-dependent Kinase 1 Specific Phosphorylation Sites by an In Vitro Kinase Assay

Published on: May 3, 2018

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Cdk1和PP2A构成了控制非典型E2Fs有序降解的分子开关

Sapir Nachum-Raines1, Noy Gamliel1, Danit Wasserman1

  • 1Faculty of Life Sciences and the Institute of Nanotechnology and Advanced Materials, Bar-llan University, Ramat-Gan 5290002, Israel.

bioRxiv : the preprint server for biology
|March 3, 2025
PubMed
概括

细胞循环的进展依赖于亚纳酶促进复合体/循环体 (APC/C) 降解关键蛋白质. 这项研究揭示了Cdk1-PP2A信号如何控制APC/C基质降解,确保细胞周期不可逆转.

关键词:
在APC/C基板上.细胞循环的细胞周期没有细胞的系统系统.E2F E2F E2F E2F E2F E2F E2F E2F E2F E2F E2F米托斯出口的出口.蛋白质降解 蛋白质降解在Ubiquitination中使用.

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Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors10:33

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