应激反应转录因子家族是玉米内核非生物应激反应的关键组成部分
Anna C H Pardo1,2, Jeremy D Pardo2,3, Robert VanBuren2,3,4
1Department of Horticulture, Michigan State University, East Lansing, MI 48824.
bioRxiv : the preprint server for biology
|March 3, 2025
概括
玉米使用744个基因的核心组来应对干旱和热等各种非生物压力. 这些基因,包括关键的转录因子,使灵活的承受压力成为可能,这对于农业适应气候变化至关重要.
科学领域:
- 植物科学 植物科学
- 基因组学就是基因组学.
- 农业科学 农业科学
背景情况:
- 生物压力 (干旱,盐,热,寒冷,洪水,低) 严重影响农业,气候变化加剧了.
- 植物经常面临多个同时或连续的非生物压力,引发重叠的分子反应.
研究的目的:
- 通过元分析,通过各种非生物性压力因素在玉米中识别核心应激基因.
- 了解玉米用于非生物应激耐受性的转录策略.
主要方法:
- 在不同的非生物压力下对近1900个公开的玉米RNAseq样本进行了元分析.
- 批量校正以减轻异质性,然后进行集操作和随机森林机器学习.
- 同表达网络分析,以确定核心基因和压力特异性基因之间的关系.
主要成果:
- 确定了744个应激反应基因的核心组,这些基因在六种主要的非生物性压力中很常见.
- 这些核心基因在转录因子 (TF) 中显著丰富,来自AP2/ERF-ERF,NAC,bZIP,HSF和C2C2-CO-like等家族.
- 同表达分析显示,核心TFs调节一般和压力特异性基因表达途径.
结论:
- 玉米表现出一种保留但灵活的转录策略,用于非生物应激反应.
- 核心TF在调节通用和压力特定路径方面发挥着关键作用,为增强压力耐受性提供了目标.
- 这些发现为培育和改造适应气候变化的玉米品种提供了资源.
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