Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Proteomics01:33

Proteomics

7.2K
A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term...
7.2K
Overview of Protein Metabolism01:21

Overview of Protein Metabolism

667
Proteins are broken down into amino acids during digestion. Unlike fats and carbohydrates, which are stored for later use, proteins are not. Instead, amino acids are either used to produce ATP through oxidation or contribute to the creation of new proteins for the growth and repair of the body. Any surplus amino acids from the diet are converted into glucose or triglycerides rather than excreted.
Amino acids play various roles in the body once they are absorbed into cells. They are restructured...
667

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Sustainable Extraction of Alkaloids from <i>Worsleya procera</i>: Improving the Method with Green Chemistry.

ACS omega·2025
Same author

Intergenerational metabolomic signatures of bleaching resistance in corals.

Nature communications·2025
Same author

Balance between bile acid conjugation and hydrolysis activity can alter outcomes of gut inflammation.

Nature communications·2025
Same author

Host metabolism balances microbial regulation of bile acid signalling.

Nature·2025
Same author

Longitudinal analyses of infants' microbiome and metabolome reveal microbes and metabolites with seemingly coordinated dynamics.

Communications biology·2024
Same author

Untargeted Metabolomic Biomarker Discovery for the Detection of Ectopic Pregnancy.

International journal of molecular sciences·2024

相关实验视频

Updated: May 24, 2025

Author Spotlight: Emerging Technologies and Advanced Tools for Decoding Metabolomics Data Analysis
07:11

Author Spotlight: Emerging Technologies and Advanced Tools for Decoding Metabolomics Data Analysis

Published on: November 10, 2023

2.2K

集群应用程序可视化,组织和导航代谢学数据.

Vinicius Hansel1, Pothuvilage Karunarathne2, Tiago Cabral Borelli1

  • 1Department of Biomolecular Sciences, Computational Chemical Biology Laboratory, School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Ribeirão Preto, Brazil.

bioRxiv : the preprint server for biology
|March 3, 2025
PubMed
概括

集群应用程序为代谢学中主要坐标分析 (PCoA) 提供了一个用户友好的网络应用程序,简化了对没有广泛生物信息学专业知识的研究人员进行集群和数据可视化.

更多相关视频

A Clinical Metaproteomics Workflow Implemented within Galaxy Bioinformatics Platform to Analyze Host-Microbiome Interactions Underlying Human Disease
09:52

A Clinical Metaproteomics Workflow Implemented within Galaxy Bioinformatics Platform to Analyze Host-Microbiome Interactions Underlying Human Disease

Published on: January 10, 2025

470
An Integrated Workflow of Identification and Quantification on FDR Control-Based Untargeted Metabolome
05:35

An Integrated Workflow of Identification and Quantification on FDR Control-Based Untargeted Metabolome

Published on: September 20, 2022

3.6K

相关实验视频

Last Updated: May 24, 2025

Author Spotlight: Emerging Technologies and Advanced Tools for Decoding Metabolomics Data Analysis
07:11

Author Spotlight: Emerging Technologies and Advanced Tools for Decoding Metabolomics Data Analysis

Published on: November 10, 2023

2.2K
A Clinical Metaproteomics Workflow Implemented within Galaxy Bioinformatics Platform to Analyze Host-Microbiome Interactions Underlying Human Disease
09:52

A Clinical Metaproteomics Workflow Implemented within Galaxy Bioinformatics Platform to Analyze Host-Microbiome Interactions Underlying Human Disease

Published on: January 10, 2025

470
An Integrated Workflow of Identification and Quantification on FDR Control-Based Untargeted Metabolome
05:35

An Integrated Workflow of Identification and Quantification on FDR Control-Based Untargeted Metabolome

Published on: September 20, 2022

3.6K

科学领域:

  • 代谢学 代谢学 代谢学
  • 生物信息学是一种生物信息学.
  • 数据可视化 数据可视化

背景情况:

  • 主要组件分析 (PCA) 在代谢学中很常见,但对于集群可视化来说是不理想的.
  • 代谢学数据需要专门的预处理和高效的可视化工具.
  • 缺乏用户友好的工具阻碍了许多研究人员进行集群分析.

研究的目的:

  • 介绍ClusterApp,这是一个用于代谢学中主要坐标分析 (PCoA) 的网络应用程序.
  • 提供一种可访问的工具,用于对代谢学数据进行聚类和可视化.
  • 为代谢学研究人员扩大聚类替代方案,超越PCA.

主要方法:

  • 集群应用程序使用QIIME 2 Docker图像进行PCoA计算和皇帝图形可视化.
  • 支持GNPS,GNPS2或用户提供的电子表格的数据输入.
  • 提供通过Docker进行本地安装或集成到Jupyter笔记本.

主要成果:

  • 分析了来自小鼠组织和珊瑚生命阶段的LC-MS/MS代谢数据集.
  • 布雷-库蒂斯不相似度有效突出了新陈代谢变异.
  • 信息通信技术规范化和自动缩放提高了聚类分辨率,并揭示了明显的样本分离.

结论:

  • 集群应用程序提供了可访问的,动态的工具,用于在代谢学探索性数据分析.
  • 用PCoA对情侣数据进行转换,用于多功能集群分析.
  • 使研究人员能够在没有高级生物信息学专业知识的情况下发现模式.