用于使用印刷电路板的OPM-MEG双平面无效卷系统
Mainak Jas1,2, John Kamataris1, Teppei Matsubara1,2
1Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, USA.
bioRxiv : the preprint server for biology
|March 3, 2025
概括
新的,负担得起的印刷电路板 (PCB) 线圈有效地消除了背景磁场,使光学磁计 (OPM) 能够在不太屏蔽的环境中用于磁脑摄影 (MEG). 这有助于推进可访问的神经科学研究.
科学领域:
- 生物物理学的生物物理.
- 神经科学是一个神经科学.
- 传感器技术 传感器技术
背景情况:
- 光学磁计 (OPM) 提供敏感的,非侵入性测量的人类电生理信号,如磁脑摄影 (MEG).
- OPMs需要接近零的背景磁场来进行准确,不扭曲的测量.
- 传统的双平面场取消线圈是昂贵的,并且很难制造.
研究的目的:
- 为基于OPM的MEG设计和制造价格实惠,易于制造的背景磁场取消线圈.
- 为了证明这些线圈在减少背景磁场方面的有效性.
- 为了使OPM-MEG在不那么严格的磁屏蔽条件下运行.
主要方法:
- 使用开源bfieldtools软件设计的双层印刷电路板 (PCB) 线圈,以取消均和梯度磁场.
- 开发了一种基于软件的方法,在PCB层之间创建连续电流路径.
- 制造的线圈分为两半,以方便制造和组装.
主要成果:
- 实现了与以前的方法 (1.3 - 7.1 nT/mA) 相当或高于现场取空线圈的效率.
- 在50厘米的球体体积内,最大的背景磁场成分从21 nT减少到2 nT.
- 在轻度屏蔽的房间中使用OPM成功记录了体感觉唤起的场 (SEF),产生了与在高度屏蔽的房间中基于SQUID的MEG相似的结果.
结论:
- 开发了一种成本效益和可制造的解决方案,用于使用PCB的背景磁场取消线圈.
- 证明了OPM-MEG在较少屏蔽环境中的可行性,扩大了可访问性.
- 将设计和软件作为一个开源包 (opmcoils) 传播,以促进OPM-MEG的采用.
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