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在体内生产工程化ACE2诱可以保护肺部免受SARS-CoV-2感染

Yuta Suzuki1, Takayuki Miyazaki1, Yoko Ida2

  • 1Tsukuba Research Laboratories, Eisai Co., Ltd., Ibaraki 300-2635, Japan.

Molecular therapy. Nucleic acids
|March 3, 2025
PubMed
概括

下一代mRNA疗法编码了一个工程化的ACE2诱,3N39v4,用于对抗快速突变的SARS-CoV-2变种. 这种新的方法在临床前模型中显示了广泛的中和和改善的结果,提供了一个有前途的紧急治疗策略.

关键词:
在ACE2诱中使用诱.在 COVID-19 疫情中,MT:寡核酸:治疗方法和应用.这就是SARS-CoV-2病毒.逃脱突变的突变是什么脂质纳米颗粒的使用方法提供mRNA的交付.在mRNA疗法中使用的mRNA疗法

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