在儿科便秘中进行结肠过境研究和结肠计量
Atchariya Chanpong1,2,3, Elizabeth Morris4,5, Teresa Di Chio1,6
1Neurogastroenterology & Motility Unit, Gastroenterology Department, Great Ormond Street Hospital for Children, London, UK.
在患有便秘的儿童中,结肠过渡扫描 (CS) 和结肠测量 (CM) 显示了直位西格缩模式和过渡时间之间的相关性. 脊柱体可能充当结肠光道过渡的守门员.
科学领域:
- 儿科胃肠病学 儿科胃肠病学
- 结直肠生理学 结直肠生理学
- 诊断成像 诊断成像 诊断成像
背景情况:
- 儿童耐火性便秘通常需要进行结肠功能调查.
- 结肠过渡光学 (CS) 和结肠测量 (CM) 评估结肠功能的不同方面.
- 有限的研究比较了儿童群体中CS和CM的发现.
研究的目的:
- 在患有耐火性便秘的儿童中,将结肠过渡光学 (CS) 和结肠力学 (CM) 相对应.
- 为了确定特定的测距图案是否预测了CS上的光线过渡结果.
主要方法:
- 对患有耐火性便秘的儿童进行了回顾性审查,他们接受了CS和CM.
- CS使用几何中心 (GC) 量化过境;被分类为正常,直垂西格等待或缓慢过境.
- CM模式被分类为正常,远端结肠动或泛结肠动.
主要成果:
- 便秘的CS和CM亚型之间没有显著的一致性.
- 6小时GC得分和直西格高幅度传播收缩 (HAPCs) 幅度 (r=0.761,p=0.007) 之间存在强烈的相关性.
- 较高的24小时上升结肠放射追踪器百分比与更多的bisacodyl诱导的HAPC相关.
结论:
- 在6小时后的光学GC显著与直交形CM参数相关.
- 直筒形结肠的收缩功能可能在调节结肠光通路中发挥关键作用.
- 这些研究结果表明,直筒形状体作为儿童大肠过境的守门员.
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