在中年和老年人群中估计的脉冲波速度和中风:来自3个潜在队列的见解
Yingzhen Gu1, Xiaorong Han1, Jinxing Liu1
1Fuwai Hospital, National Center for Cardiovascular Diseases, National Clinical Research Center for Cardiovascular Diseases Chinese Academy of Medical Science and Peking Union Medical College Beijing China.
Journal of the American Heart Association
|March 3, 2025
概括
较高的估计脉冲波速度 (ePWV),衡量动脉硬度,与老年人中风风险增加有关. 这一发现可能有助于改善中风预防策略.
科学领域:
- 心血管研究的心血管研究.
- 流行病学 流行病学
- 老年学是一门学科.
背景情况:
- 动脉硬是中风的新兴危险因素.
- 估计脉冲波速度 (ePWV) 与老年人中风之间的关系需要进一步调查.
研究的目的:
- 调查EPWV和中风事件在中年和老年人的多样化,全国代表性队列之间的关联.
- 为了确定ePWV是否可以作为中风风险的预测指标.
主要方法:
- 利用了三大前性队列的数据:健康与退休研究 (美国),英国老龄化纵向研究 (英国) 和中国健康与退休纵向研究 (中国).
- 使用年龄和平均动脉压计算的ePWV.
- 采用考克斯的比例危险模型来分析ePWV和中风发病率之间的关联.
主要成果:
- 分析包括三个队伍中的25,000多名参与者.
- 在所有队列中,在较高的ePWV水平和发生中风风险增加之间发现了显著的关联.
- 在所有研究中,中风风险比率从1.20到1.37不等,表明存在一致的联系.
结论:
- 升高的ePWV与中年和老年人群中风风险更高有关.
- 通过ePWV评估,可以提高初级中风预防和治疗策略.
- 这项研究强调了动脉硬在心血管风险评估中的重要性.
相关概念视频
Special considerations while measuring pulse
551
Assessing a patient's pulse is a fundamental skill in healthcare, but certain situations require special attention:
551
Pulse amplitude and quality
1.6K
Pulse amplitude is a crucial indicator of cardiac health because it provides valuable insights into the strength of left ventricular contractions and the overall uniformity of blood circulation within the vasculature. The strength of the pulse is directly related to the force with which the heart contracts and the volume of blood being pumped.
A weak or absent pulse may indicate reduced cardiac output or poor left ventricular contraction, which can be signs of cardiovascular dysfunction or...
A weak or absent pulse may indicate reduced cardiac output or poor left ventricular contraction, which can be signs of cardiovascular dysfunction or...
1.6K
Pulse
412
When the heart pumps blood out, arterial elastic fibers play a crucial role in sustaining a high-pressure gradient. They expand to accommodate the received blood and then recoil - a process known as the pulse that can be either manually palpated or electronically quantified. Despite a reduction in its effect with increased distance from the heart, elements of the pulse's systolic and diastolic components persist, observable even at the arteriole level.
The pulse serves as a clinical...
The pulse serves as a clinical...
412
Pulse Assessment Sites
884
Pulse assessment sites are crucial in evaluating a patient's cardiovascular health. By assessing the pulsations of arteries at specific anatomical locations, healthcare professionals can gather valuable information about blood flow, heart rate, and peripheral circulation. Understanding these pulse assessment sites is essential for conducting comprehensive cardiovascular evaluations and monitoring patients' overall health. These sites are strategically chosen due to the accessibility and...
884
Blood Pressure
2.8K
The movement of blood in a human body, commonly referred to as blood flow, is determined by the volume of blood that traverses a certain section of the bodily system per unit time. It is the rhythmic contraction of the heart's ventricles that primarily instigates this movement. As the ventricles contract, blood is forced into the prominent arteries, which then flow from areas of greater pressure to lower pressure areas. This movement continues into smaller arteries and arterioles and...
2.8K
Assessing Blood pressure using a doppler ultrasound
1.2K
To obtain accurate blood pressure measurements in clinical settings, especially when traditional methods are insufficient, healthcare professionals utilize the Doppler ultrasound technique. This method uses high-frequency sound waves to detect blood flow within the arteries, which is crucial for patients with conditions that complicate circulatory system assessment.
Pre-Procedural Guidelines for Doppler Ultrasound Blood Pressure Assessment:
Preparation of Equipment:
Pre-Procedural Guidelines for Doppler Ultrasound Blood Pressure Assessment:
Preparation of Equipment:
1.2K


