机械通风COVID-19患者的倾斜定位的结果
Jonathan K Chandler1, Badr Jandali1, Katie Joyce1
1Dr. Chandler, Jandali, Joyce, Smith, and Brownback are affiliated with Division of Pulmonary Disease, Critical Care and Sleep Medicine, The University of Kansas School of Medicine, Kansas City, Kansas, USA.
Respiratory care
|March 3, 2025
概括
机械通风COVID-19患者的倾斜定位与ARDS降低了再灌输率. 这种干预需要增加神经肌肉阻塞和镇静,但显示了类似的ICU停留和30天的结果.
科学领域:
- 临界护理医学 临界护理医学
- 肺部病理学 肺部病理学
- 传染性疾病 传染性疾病
背景情况:
- 已知躺卧可以降低严重ARDS患者的死亡率.
- COVID-19可能会导致严重的呼吸衰竭和ARDS,需要进一步调查proning的有效性.
- 虽然在COVID-19患者中越来越多地使用proning,但需要更多的数据.
研究的目的:
- 为了评估在机械通风COVID-19患者的ARDS容易定位的实用性和结果.
- 为了比较预科和非预科COVID-19 ARDS患者之间的再灌输率和其他临床结果.
主要方法:
- 一个单一中心的回顾性研究,对100名连续的COVID-19患者进行了ARDS,需要机械通风.
- 每天收集7天的数据,包括30天的结果.
- 53名预备受试者与47名未预备受试者进行了比较.
主要成果:
- 预备受试者BMI较高,初始P/F比较低,但基线特征其他方面相似.
- 预先治疗的患者获得了更多的神经肌肉阻塞和更高的镇静水平.
- 重新输卵率显着较低的proned组 (1.9%对19.1%).
- 在28.3%的受试者中,发生了与相关的并发症.
结论:
- 机械通风COVID-19 ARDS患者的倾斜定位与增加神经肌肉阻塞和镇静的使用有关.
- 普隆与呼吸衰竭的再灌输率显著降低有关.
- 结局,如ICU停留和30天死亡率在各组之间是相似的.
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