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Updated: Jun 15, 2025

A Method to Study the C924T Polymorphism of the Thromboxane A2 Receptor Gene
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A Method to Study the C924T Polymorphism of the Thromboxane A2 Receptor Gene

Published on: April 1, 2019

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鉴定与普拉瓦斯塔丁和皮塔瓦斯塔丁相关的遗传变异 药理动力学

Anssi J H Mykkänen1,2,3, E Katriina Tarkiainen1,2,3, Suvi Taskinen1,3

  • 1Department of Clinical Pharmacology, University of Helsinki, Helsinki, Finland.

Clinical pharmacology and therapeutics
|March 3, 2025
PubMed
概括

在SLCO1B1的遗传变异显著影响普拉瓦斯塔丁和皮塔瓦斯塔丁的药物暴露. 特定的SLCO1B1和CYP2C9基因型改变了个体处理这些他类药物的方式,影响了他们的药理学特征.

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