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Updated: May 24, 2025

Synthesis of Masarimycin, a Small Molecule Inhibitor of Gram-Positive Bacterial Growth
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无法修复:TA系统 ParE 毒素通过有效的陀螺酶抑制而无需驱动电阻

Chih-Han Tu1, Shengfeng Ruan1, Michelle Holt1

  • 1Department of Chemistry and Biochemistry, University of Oklahoma, Norman, Oklahoma, USA.

Journal of bacteriology
|March 3, 2025
PubMed
概括

来自各种细菌的ParE毒素抑制了DNA旋转酶,增加了突变率,但没有导致抗生素耐药性. 这表明ParE毒素可能是新一类抗菌剂.

关键词:
帕尔埃毒素是一种毒素.对抗微生物的敏感性.细菌细胞的生存能力.酶抑制可以抑制陀螺酶.突变的频率是变化的频率.毒素抗毒素是一种毒素.

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