心肌功能障碍和长期COVID的风险在从轻度和中度COVID-19中恢复过来的患者中
Binyu Zhou1, Yiran Zhang1, Shuang Han1
1Department of Medical Ultrasound, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan, China.
Echocardiography (Mount Kisco, N.Y.)
|March 3, 2025
概括
在COVID-19后持续的心血管症状与微妙的心肌功能障碍有关. 特定的心声回声测量,包括左心房管应变和基底内左心室纵向应变,预测症状的持续性.
科学领域:
- 心脏病学 心脏病学
- 传染性疾病 传染性疾病
- 医疗成像医学成像
背景情况:
- 持续的心血管症状在COVID-19幸存者中很常见.
- 心肌功能障碍的程度及其COVID-19后预测因素需要进一步阐明.
研究的目的:
- 在康复的COVID-19患者中评估心肌功能障碍.
- 为了确定持续性心血管症状的预测因素.
主要方法:
- 分析了546名康复的COVID-19患者和351名对照者的心声图.
- 评估了心肌应变参数,包括左心室全球纵向应变 (LVGLS),区域LVLS和左心房应变 (LAS).
- 12个月后的临床随访发现了持续的症状;多变量逻辑回归确定了预测因素.
主要成果:
- 虽然LVGLS保持稳定,但区域LVLS和LAS在COVID-19后显著减少.
- 16.5%的患者在1年的随访中报告了持续的心血管症状.
- 拉萨导管菌株和基底受体 LVLS 独立地与持久症状相关.
结论:
- 亚临床心肌功能障碍,以区域LVLS损伤和LAS减少为特征,在COVID-19后持续存在.
- 拉斯维加斯管菌株和基底下的LVLS是风险分层的新型成像标志物.
- 这些发现支持针对性的心声回声监测和在COVID后护理中的早期干预.
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