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在美国黑人人口中的新用户中,对结直肠癌查的mt-sDNA测试的坚持

Mallik Greene¹, Shrey Gohil¹, Mark Camardo¹

¹Exact Sciences Corporation, Madison, Wisconsin, USA.

Current medical research and opinion

|March 3, 2025

概括

这项研究发现,62.0%的黑人个人坚持多目标便DNA (mt-sDNA) 测试以进行结肠直肠癌查. 在女性,老年人和通过数字外展接触的人群中观察到更高的坚持.

科学领域:

在瘤学瘤学.
公共卫生公共卫生
遗传学遗传学是一个

背景情况:

结肠直肠癌 (CRC) 不成比例地影响美国的黑人,需要有效的查策略.
多目标便DNA (mt-sDNA) 测试为CRC查提供了一个非侵入性的选择.

研究的目的:

评估美国黑人患者对mt-sDNA测试的坚持率.
为了确定与mt-sDNA测试依从性相关的人口统计和外展相关因素.

主要方法:

对2017年1月至2023年12月的索赔数据进行回顾性队列分析.
纳入标准:年龄在45岁以上的黑人患者;排除标准:特定的付款人类型和过期处方.
坚持定义为在365天内返回有效的测试套件;用于识别坚持预测因素的后勤回归.

主要成果:

在434,951名黑人患者中,对mt-sDNA测试的总体遵守率为62.0%.
较高的坚持与女性性别,年龄 (76岁以上) 和非大都市居住 (所有p < 0.001) 相关.
数字外展 (短信/电子邮件组合) 和来自胃肠道专家的订单显著改善了遵守 (OR = 1.25和OR分别在0.38-0.54之间;所有p < 0.001).

结论:

在全国大批黑人群体中观察到62.0%的mt-sDNA测试坚持率.
诸如女性性别,年龄较大,非大都市位置和数字外展等因素对坚持产生了积极的影响.
mt-sDNA测试显示了改善CRC查在不同人群中的前景,这需要进一步调查.

关键词:

坚持的坚持坚持的坚持非洲裔美国人.结肠直肠癌查结肠直肠癌查在健康方面存在差异.进行mt-sDNA测试.

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