双相情绪障碍青少年的认知功能和社会认知:躁狂发作和缓解期之间的比较
Celal Yeşilkaya1, Sezen Alarslan2, Mustafa Tuncturk3
1Department of Child and Adolescent Psychiatry, Konya Ereğli State Hospital, Konya, Turkey. celalyesilkaya94@gmail.com.
概括
躁狂期间早期出现的双极性障碍 (EBD) 与缓解相比,在社交认知,处理速度,抑制和注意力方面表现出显著的认知缺陷. 这些障碍凸显了针对性神经认知干预的必要性.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 认知心理学 认知心理学
背景情况:
- 早期出现的双相情感障碍 (EBD) 具有显著的认知功能障碍.
- 了解躁狂发作和缓解期间的认知障碍对于有效治疗至关重要.
研究的目的:
- 为了比较EBD患者在躁狂发作和缓解期间的认知表现.
- 评估特定的认知领域,包括记忆,注意力和社会认知.
主要方法:
- 评估了95名EBD患者 (55名躁狂,40名缓解) 和30名健康对照 (HC) 的队列.
- 一个全面的认知电池评估了口头/视觉记忆,注意力,抑制,解决问题,工作记忆,处理速度,口头流性和思维理论 (ToM).
- 计算了全球认知功能,并在缓解期间重新评估了躁狂患者.
主要成果:
- 与缓解期患者相比,在躁狂发作中的EBD患者表现出处理速度,注意力,抑制和全球认知功能的中度损伤.
- 与健康对照组相比,缓解期的个体在口头记忆,工作记忆,ToM,处理速度,解决问题,注意力,抑制和视觉记忆方面表现较差.
- 在躁狂发作期间,社会认知,处理速度,抑制和注意力的障碍更加明显.
结论:
- 认知缺陷,特别是在社会认知,处理速度,抑制和注意力方面,在EBD躁狂发作期间更为严重.
- 研究结果强调需要药理和心理治疗干预措施,以针对EBD中神经认知缺陷.
- 进一步的研究应该探索治疗策略,以改善EBD患者的认知功能.
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