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Updated: May 24, 2025

Adoptive Immunotherapy of iNKT Cells in Glucose-6-Phosphate Isomerase G6PI-Induced RA Mice
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缺少SIRT3会减少PFKFB3驱动的T细胞糖解,并促进关节炎炎症

Ting-Ting Wang1,2,3,4, Taotao Han2,5, Xinyue Xiao6

  • 1Clinical Biobank, Institute of Clinical Medicine, National Infrastructures for Translational Medicine, State Key Laboratory of Complex, Severe, and Rare Diseases, Peking Union Medical College Hospital, Beijing, China.

Science China. Life sciences
|March 3, 2025
PubMed
概括

赛尔图因3 (SIRT3) 缺乏会损害T细胞糖解和ATP的产生,恶化小鼠的类风湿性关节炎 (RA) 和抗原诱导性关节炎 (AIA). 恢复PFKFB3表达可以减轻这些影响.

关键词:
在SIRT3中,SIRT3是SIRT3.在T细胞,T细胞.代谢过程中的代谢.类风湿性关节炎 类风湿性关节炎

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