B.

Yue Xu1,2, Chun Yang3, Yingyue Zeng4

  • 1State Key Laboratory of Membrane Biology, School of Life Sciences, Institute for Immunology, China Ministry of Education Key Laboratory of Protein Sciences, Beijing Advanced Innovation Center for Structural Biology, Beijing Key Lab for Immunological Research on Chronic Diseases, Tsinghua University, Beijing, China.

概括

这项研究详细介绍了B淋巴细胞如何使用肌二介导的引力来在激活过程中区分抗原特性. 它为B细胞研究中的引力显微镜 (TFM) 提供了优化的实验条件.

相关概念视频

Tension Response at Adherens Junctions01:26

Tension Response at Adherens Junctions

The adherens junctions that anchor cells together are multi-protein complexes that dynamically adapt to mechanical stimuli such as tensile forces and shear stress. Mechanosensory proteins in these junctions can sense such mechanical stimuli and undergo a shift in their conformation, resulting in an altered function — a process called mechanotransduction.
α-Catenin as a Mechanosensory Protein
The α-catenin of adherens junctions is an allosteric protein with three VH (vinculin...
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