菌毒素和氧化油对肉肠道微生物群的调节作用
Kouassi R Kpodo1, Daniel J Milliken1, Philip M Campos1
1Animal Biosciences and Biotechnology Laboratory, Agricultural Research Service, United States Department of Agriculture, Beltsville, Maryland, United States of America.
PloS one
|March 3, 2025
概括
料中的菌毒素和氧化油显著改变肠道微生物群,影响细菌多样性和代谢途径,对家禽健康和生产产生潜在影响.
科学领域:
- 禽畜科学 禽畜科学 禽畜科学
- 微生物学 微生物学
- 动物营养 动物营养
背景情况:
- 气候变化和替代料成分将菌毒素和氧化油引入家禽的饮食中.
- 这些污染物可以差异地影响肉的肠道微生物群.
- 了解这些影响对于保持家禽健康和生产率至关重要.
研究的目的:
- 研究受菌毒素污染的玉米和氧化油对肉肠道微生物群的个体和相互作用作用.
- 分析对乳房和乳房微生物群落的影响以及预测的代谢功能.
- 为了确定受这些饮食挑战影响的特定细菌种群和途径.
主要方法:
- 肉被食了21天的受菌毒素污染的玉米和/或氧化油的饮食.
- 用16S rRNA基因测序 (V3-V4区域) 来测序来自阴茎和阴茎样本的细菌DNA.
- 进行了生物信息和统计分析,以评估微生物多样性,丰度和预测的途径.
主要成果:
- 暴露于毒素,特别是氧化油,增加了微生物丰富性和质含量的均性.
- 贝塔多样性分析表明,在叶含量中,微生物社区结构发生了变化.
- 特定的细菌种群 (例如,Streptomyces,Escherichia-Shigella) 和代谢途径 (例如,RNA/DNA合成,氧化还原调节,糖解,氨基酸降解) 受到显著影响.
结论:
- 菌毒素和氧化油,单独和相互作用,显著影响肉肠道微生物群的组成和功能.
- 膜似乎是微生物改变的主要部位.
- 观察到的变化,包括增加的Streptomyces (潜在的排毒) 和Escherichia-Shigella (与生长负相关),突出了影响鸟类健康的复杂相互作用.
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