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Updated: May 24, 2025

Measuring Mitochondrial Function of Naïve and Effector CD8 T Cells
06:07

Measuring Mitochondrial Function of Naïve and Effector CD8 T Cells

Published on: March 28, 2025

185

通过NAE1介导的化作为对效应细胞CD8+T细胞的重要翻译后修饰检查点

Jiacheng Jin1,2, Ruohan Zhang3, Jianying Li1,2

  • 1Pelotonia Institute for Immuno-oncology, Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute, College of Medicine, The Ohio State University, Columbus, OH 43210.

Proceedings of the National Academy of Sciences of the United States of America
|March 3, 2025
PubMed
概括

蛋白质修饰的内滴化对于CD8+T细胞激活和抗瘤免疫是必不可少的. 增强神经前体细胞发育下调蛋白8激活酶E1 (NAE1) 增强T细胞功能对抗癌症.

关键词:
在T细胞,T细胞.免疫疗法 免疫疗法翻译后的修改 翻译后的修改

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