相关实验视频

Updated: May 24, 2025

Swin-PSAxialNet: An Efficient Multi-Organ Segmentation Technique
04:48

Swin-PSAxialNet: An Efficient Multi-Organ Segmentation Technique

Published on: July 5, 2024

348

三CvT-DTI:使用三模态表示和卷积视觉转换器预测药物向相互作用

Azouz Maroua, Gang Tian, Rui Wang

    IEEE journal of biomedical and health informatics
    |March 3, 2025
    PubMed
    概括

    通过整合各种药物特征,TriCvT-DTI提高了药物向相互作用的预测. 这种深度学习模型提高了药物发现和重新定位的准确性和概括性.

    更多相关视频

    A Swin Transformer-Based Model for Thyroid Nodule Detection in Ultrasound Images04:23

    A Swin Transformer-Based Model for Thyroid Nodule Detection in Ultrasound Images

    Published on: April 21, 2023

    1.7K
    Diagonal Method to Measure Synergy Among Any Number of Drugs12:08

    Diagonal Method to Measure Synergy Among Any Number of Drugs

    Published on: June 21, 2018

    18.4K

    相关概念视频

    Targets for Drug Action: Overview01:26

    Targets for Drug Action: Overview

    Drugs target macromolecules to modify ongoing cellular processes. Primary drug targets include receptors, ion channels, transporters, and enzymes.
    Receptors are either membrane-spanning or intracellular proteins, which upon binding a ligand, get activated and transmit the signal downstream to elicit a response. Drugs bind receptors, either mimicking the action of endogenous ligands or blocking the receptor activity to bring about a modified response. Nearly 35% of approved drugs target the G...
    6.0K
    Combined Effects of Drugs: Synergism01:27

    Combined Effects of Drugs: Synergism

    Synergism is a useful mechanism where combining two or more drugs is more effective than each constituent used alone. Such combinations are also called supra-additive interactions. The drugs collectively enhance the final therapeutic effect by acting on different targets. Another advantage is that the low dose of each constituent drug is sufficient to achieve the desired effect. This helps reduce the duration of therapy and lower the adverse effects of these drugs.
    Such synergistic combinations...
    3.7K
    Drug-Receptor Interactions01:29

    Drug-Receptor Interactions

    Drug-receptor interaction describes the binding of receptors by drugs, but not all drug-receptor interactions result in activation and tissue response. For instance, the binding of agonists activates the receptor to generate a cellular reaction, while antagonists bind to receptors without causing their activation.
    Several parameters, such as the drug's affinity for its receptor and its efficacy, which is its ability to activate the receptor, determine the drug's effect on the tissue....
    4.8K
    Drug Discovery: Overview01:26

    Drug Discovery: Overview

    Drug discovery is a multifaceted process involving extensive screening, testing, and optimization of lead compounds to identify potential new drugs for therapeutic use. It combines several approaches, including screening large numbers of natural products, chemical modification of known active molecules, identification of new drug targets, and rational design based on biological mechanisms and drug-receptor structure. These approaches are carried out in both academic research laboratories and...
    7.3K
    Combined Effects of Drugs: Antagonism01:30

    Combined Effects of Drugs: Antagonism

    The combined effects of drugs can result in various interactions, of which an important type is antagonism. Antagonism is a mechanism where one drug inhibits or counteracts the effects of another drug. Antagonism can occur through various means, including receptor binding, allosteric modulation, functional interaction, chemical reactions, and pharmacokinetic processes.
    The most common type is receptor antagonism, where one drug acts as an antagonist to block the effects of another drug by...
    8.2K
    Multicompartment Models: Overview01:14

    Multicompartment Models: Overview

    Multicompartment models are mathematical constructs that depict how drugs are distributed and eliminated within the body. They segment the body into several compartments, symbolizing various physiological or anatomical areas connected through drug transfer processes such as absorption, metabolism, distribution, and elimination.
    These models offer a more comprehensive representation of drug behavior in the body than one-compartment models. They accommodate the complexity of drug distribution,...
    79