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Updated: Jun 19, 2026

Efficient Derivation of Human Neuronal Progenitors and Neurons from Pluripotent Human Embryonic Stem Cells with Small Molecule Induction
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Efficient Derivation of Human Neuronal Progenitors and Neurons from Pluripotent Human Embryonic Stem Cells with Small Molecule Induction

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一种简化方法,用于长期维护人类诱导的多能干细胞衍生神经网络

Shravan Thaploo, Derrick Lin, Yongcheng Li

    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
    |March 3, 2025
    PubMed
    概括

    研究人员开发了一种用于长期培养人类神经网络的新方法. 这种技术支持超过90天的活跃神经网络活动,无需使用动物产品或基因改造.

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    Long-term Potentiation01:35

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    Long-term potentiation, or LTP, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTP is the process of synaptic strengthening that occurs over time between pre- and postsynaptic neuronal connections. The synaptic strengthening of LTP works in opposition to the synaptic weakening of long-term depression (LTD) and together are the main mechanisms that underlie learning and memory.
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