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Updated: Jul 14, 2026

Molecular Profiling of the Invasive Tumor Microenvironment in a 3-Dimensional Model of Colorectal Cancer Cells and Ex vivo Fibroblasts
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STFormer:学习探索空间转录学的点关系从结肠直肠癌组织学预测结肠直肠癌

Gan Zhan, Xiuju Du, Jing Liu

    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
    |March 3, 2025
    PubMed
    概括

    从组织学图像中预测空间转录组学 (ST) 是一个具有成本效益的替代方案. 新的深度学习模型STFormer通过解决污点变异和增强点间相关性来改善ST预测.

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    Tumor Progression02:07

    Tumor Progression

    Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
    Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...