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相关概念视频

Confocal Fluorescence Microscopy01:16

Confocal Fluorescence Microscopy

Confocal microscopy is an advanced microscopic technique. The prime advantage of the confocal microscope over other microscopy techniques is its ability to block the out-of-focus light from the illuminated samples using pinholes. It is widely used with fluorescence optics to obtain high-resolution, sharp contrast images. Unlike optical microscopes, confocal microscopes use a focused beam of light laser to scan the entire sample surface at different z-planes. These microscopes are, therefore,...
Three-Dimensional Microscopy in Microbiology01:28

Three-Dimensional Microscopy in Microbiology

Three-dimensional imaging techniques are essential in cell biology, allowing researchers to visualize intricate cellular structures with high resolution. Two prominent methods, Differential Interference Contrast Microscopy (DIC) and Confocal Scanning Laser Microscopy (CSLM), provide distinct advantages for imaging live and thick specimens, respectively.Differential Interference Contrast MicroscopyDIC microscopy enhances contrast in transparent, unstained samples by converting phase...

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相关实验视频

Updated: Jul 12, 2026

Real-time Monitoring of High Intensity Focused Ultrasound HIFU Ablation of In Vitro Canine Livers Using Harmonic Motion Imaging for Focused Ultrasound HMIFU
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在3D超声波成像中,用于镜头式行列阵列的光束构造器.

Ali Salari, Melanie Audoin, Borislav Gueorguiev Tomov

    IEEE transactions on ultrasonics, ferroelectrics, and frequency control
    |March 3, 2025
    PubMed
    概括

    这项研究引入了一种新型的射线追踪束变换器,以改善超声波成像. 新方法显著提高了镜头的行列阵列的分辨率和对比度,克服了以前薄镜头模型的局限性.

    科学领域:

    • 超声波成像 超声波成像
    • 医疗器械 医疗器械 医疗器械 医疗器械
    • 声波波束形成 声波波束形成

    背景情况:

    • 行列 (RC) 数组具有有限的视野 (FOV).
    • 现有的薄透镜模型用于透镜RC阵列,导致飞行时间 (TOF) 计算中的不准确性,降低图像质量.
    • 这限制了RC阵列在各种成像场景中的实际应用.

    研究的目的:

    • 开发和验证一种用于透镜RC阵列的新型光束变频器,它克服了薄透镜模型的局限性.
    • 为了提高飞行时间 (TOF) 计算的准确性,使用射线跟踪进行增强的超声波成像.
    • 在超声波成像中,以提高分辨率和对比度来实现更广泛的视野 (FOV).

    主要方法:

    • 实施了一种使用光线跟踪进行精确TOF计算的新型光束变频器.
    • 一台Verasonics Vantage 256扫描仪与Vermon RC探头一起用于数据采集.
    • 合成孔径超声波序列被用于特定配置的虚拟源和活性元素.

    主要成果:

    • 射线追踪方法显著提高了侧面分辨率,比双圆柱形镜头的薄透镜模型提高了4.6倍.
    • 使用新方法,图像对比度从23.1提高到29.8dB,同时保持视野 (FOV).

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  • 测试了球形和双形透镜 (聚乙烯和PMMA),分别产生了20°和33°的FOV.

    • 结论:

    • 拟议的射线追踪光束制造器准确计算TOF,从而在带镜头的RC超声波阵列中获得更高的分辨率和对比度.
    • 这一进步有效地解决了薄镜头模型的局限性,使得更广泛的FOV成像成为可能.
    • 开发的方法为需要高分辨率,宽FOV成像的超声波应用提供了显著的改进.