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在高海拔暴露后,健康成年人的 Fundus 变化

Jiaxin Li¹, Yunzhu Kong¹, Peiyu Wang¹

¹Tianjin Key Laboratory of Retinal Functions and Diseases, Tianjin Branch of National Clinical Research Center for Ocular Disease, Eye Institute and School of Optometry, Tianjin Medical University Eye Hospital, Tianjin, 300384, China.

Photodiagnosis and photodynamic therapy

|March 3, 2025

概括

在健康的成年人中,长期高空暴露不会导致视力敏度变化,但会导致视网膜厚度和血管密度下降. 内视网膜和神经纤维层厚度呈现上升趋势,观察到输液面积增加.

科学领域:

眼科医生眼科眼科
高空生理学高空生理学
医疗成像医学成像

背景情况:

长期高空 (HA) 暴露会影响眼睛健康.
了解这些变化对于管理高海拔眼科医症至关重要.

研究的目的:

量化高海拔暴露对健康成年人底部的长期影响.
建立预防和治疗高海拔眼科病的参考标准.

主要方法:

使用扫描源光学连贯性断层扫描/血管学 (SS-OCT/SS-OCTA) 对15名健康参与者的30只眼睛在平原暴露前后进行了测试.
评估最佳校正的视力敏度 (BCVA),视网膜厚度 (ReT),内外ReT,神经纤维层厚度 (RNFLT),状细胞内部状层厚度 (GCIPLT),血管密度 (VD), perfusion area (PA),胆道血管体积 (CVV) 和胆道血管度指数 (CVI).
使用通用估计方程 (GEE) 进行统计分析.

主要成果:

没有观察到视敏度 (P > 0.05) 的显著变化.
在所有象限中都注意到降低了ReT,外部ReT,GCIPLT和VD (P > 0.05).
内部RET和RNFLT显示上升趋势 (P>0.05),而PA在视网膜,内视网膜,SCP和ICP显著增加 (P <0.05).

结论:

对高海拔地区的系统性适应导致了基金的结构和功能变化.
需要进一步进行大规模的纵向研究来证实这些发现并提供更明确的数据.

关键词:

基金基金基金基金基金基金基金高海拔高度的高海拔地区.光学连贯性断层扫描-血管学 perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion 充血區域是一個非常重要的區域,它是一個非常重要的區域,它是一個非常重要的區域.视网膜的厚度视网膜的厚度船舶流量密度船舶流量密度

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