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Updated: May 24, 2025

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肌肉骨接口工程中的3D打印:目前的进展和未来的方向

Tianpeng Xu1, Jingdong Rao1, Yongyi Mo1

  • 1Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong Special Administrative Region.

Advanced drug delivery reviews
|March 3, 2025
PubMed
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三维 (3D) 打印为肌肉骨组织再生提供了先进的仿生支架,解决了传统治疗受伤和疾病的局限性. 这项技术可以实现精确的制造,以改善关键组织接口的集成和功能.

科学领域:

  • 生物材料科学 生物材料科学
  • 组织工程是组织工程.
  • 整形外科医学 整形外科医学

背景情况:

  • 肌肉骨组织接口对于功能至关重要,但通常会因受伤和疾病而受损.
  • 传统的治疗方法在复杂的接口恢复方面扎.
  • 三维 (3D) 打印成为制造生物模拟支架的有希望的解决方案.

研究的目的:

  • 审查3D打印在为肌肉骨组织接口创建支架中的应用.
  • 要突出先进的技术,如多材料打印,生物打印和4D打印.
  • 讨论临床翻译的挑战和未来前景.

主要方法:

  • 审查最先进的3D打印技术 (挤出,喷墨,激光辅助生物打印).
  • 强调模仿自然组织梯度和生物材料选择.
  • 讨论在软骨-骨,椎间盘,肌/带-骨和肌肉-肌结合工程中的应用.

主要成果:

  • 通过3D打印,可以精确地制造出具有定制机械和生物特性的支架.
  • 先进的技术有助于创建复杂的结构,模仿自然组织梯度.
  • 成功的应用表明了在各种肌肉骨接口中改善整合和功能的潜力.
关键词:
通过3D打印打印3D打印.生物材料是一种生物材料.药物输送是药物输送的过程.肌肉骨的接口 肌肉骨的接口再生医学是一种再生医学.脚手架是一个脚手架.组织工程是组织工程.

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结论:

  • 3D打印在骨科医学和组织再生方面具有变革性的潜力.
  • 解决材料开发,打印分辨率和体内性能方面的挑战对于临床翻译至关重要.
  • 未来的研究方向包括整合生物材料,药物输送和先进的印刷技术.