通过虚拟患者拥抱医学的未来
Ken Wang1, Neil John Parrott1, Thierry Lavé2
1Pharma Early Research and Development, Roche Innovation Center Basel, F. Hoffmann-La Roche, Grenzacherstrasse 124, 4070 Basel, Switzerland.
虚拟患者,集成计算方法和人工智能,正在彻底改变制药研发和医疗保健. 它们使得更快,更具预测性的研究和个性化医疗成为可能,以提高药物疗效和患者的治疗结果.
科学领域:
- 计算生物学是一种计算生物学.
- 药理学 药理学是指药理学的学科.
- 数字健康数字健康
背景情况:
- 制药行业在研发生产率和个性化医疗方面面临着挑战.
- 目前的医疗保健系统寻求更有效和以患者为中心的治疗策略.
研究的目的:
- 探索虚拟患者在制药研发和医疗保健中的变革潜力.
- 突出虚拟患者如何推动以患者为中心的方法和个性化医疗.
主要方法:
- 集成计算方法,人工智能 (AI) 和先进的体外人体模型系统.
- 开发和应用虚拟患者模型用于药物开发和临床实践.
主要成果:
- 虚拟患者加速并提高了研发过程的可预测性.
- 通过与虚拟患者精确的药物剂量和时间安排,可以实现个性化医疗保健.
- 现实世界的例子显示了药物开发和临床结果的显著改善.
结论:
- 虚拟患者为改变研发和临床实践提供了巨大的潜力.
- 他们为个性化和高效的药物研发和医疗保健的新时代铺平了道路.
- 解决数据变化,监管合规和隐私方面的挑战对于广泛采用至关重要.
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