成年双边初级B-淋巴细胞淋巴瘤的丸
Gerald Mak1,2, Kenneth Chew3,2, Dale Ian Wood2
1School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Sydney, New South Wales, Australia chinhogerald.mak@health.nsw.gov.au.
BMJ case reports
|March 3, 2025
概括
本案例研究详细介绍了一例罕见的双侧丸B-淋巴细胞淋巴瘤在一个成年男性. 它强调了管理这种不常见的白血病/淋巴瘤影响两个丸的挑战.
科学领域:
- 在瘤学瘤学.
- 血液学 血液学 血液学
- 尿道瘤学 尿道瘤学
背景情况:
- 在成年人中,B-淋巴细胞白血病/淋巴瘤 (B-ALL) 是罕见的.
- 在B-ALL中,丸的参与通常是单边的.
- 双边丸干扰在成年B-ALL中异常罕见.
研究的目的:
- 报告一个单一的双边丸B-淋巴细胞淋巴瘤在成年人的病例.
- 讨论这种罕见疾病的诊断和管理策略.
- 提供有关双侧丸透成年B-ALL临床过程和治疗的数据.
主要方法:
- 无痛阴囊胀的临床表现和初始症状.
- 诊断成像:阴囊超声波.
- 组织病理学确认:根基切除术和丸活检.
- 阶段性调查:骨髓活检和外周血液检测.
- 治疗反应评估:化疗和随后的手术干预.
主要成果:
- 通过超声波证实了右丸的完整瘤透和左丸的显著透.
- 组织病理学证实了两个丸的B-淋巴细胞白血病/淋巴瘤.
- 最初的分期检测没有显示出系统性骨髓或外周血液的参与.
- 在诱导化学疗法后,左丸的持续性疾病需要进行逆侧带切除术.
结论:
- 双边丸因B型淋巴细胞淋巴瘤而受到影响,在成年人中可能发生,尽管很少发生.
- 管理需要一个多学科的方法,可能包括化疗和双边花切除术.
- 这一案例补充了双边丸疾病的成年B-ALL有限文献,为未来的治疗策略提供了信息.
相关概念视频
Disorders of the Male Reproductive System
289
Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
289
Testes: Histology
622
A tough, fibrous membrane, the tunica albuginea, covers the testes, extending inward to form fibrous partitions or septa, dividing them into internal compartments called lobules. Each lobule has 1 to 3 tightly coiled seminiferous tubules where sperm production occurs. These tubules merge into a tubular network at the back of the testis, known as the rete testis. It connects to 15 to 20 efferent ductules, leading to the epididymis.
The spermatogenic cells, responsible for producing sperm, are...
The spermatogenic cells, responsible for producing sperm, are...
622
Testes: Gross Anatomy
1.5K
The testes, also known as testicles, are the male gonads. They are housed within the scrotum, a sac-like structure located beneath the penis. The scrotum's primary role is to regulate the temperature of the testes, which is crucial for sperm production.
Each testis is surrounded by the tunica albuginea, a dense connective tissue layer that provides structural support and protection. This layer is covered by an outer serous membrane called the tunica vaginalis, which helps reduce friction...
Each testis is surrounded by the tunica albuginea, a dense connective tissue layer that provides structural support and protection. This layer is covered by an outer serous membrane called the tunica vaginalis, which helps reduce friction...
1.5K


