皮肤结核病及其人体免疫缺陷病毒阴性患者的多形呈现:一个病例报告
Rose Ekambi Kotto1, Grace Anita Nkoro2, Coralie Reine Mendouga Menye2
1Faculty of Medicine and Pharmaceutical Sciences, University of Douala, Douala, Cameroon. rozkotto25@yahoo.fr.
Journal of medical case reports
|March 3, 2025
概括
皮肤结核病虽然很少见,并且在HIV阴性个体中经常被低诊断,但呈现出各种皮肤表现. 早期考虑这种诊断对于有效的治疗和有利的结果至关重要.
科学领域:
- 皮肤病学 皮肤病学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 皮肤结核病 (TB) 不常被诊断出,特别是在人类免疫缺陷病毒阴性患者中,因为在流行地区的临床表现和诊断挑战各不相同.
- 包括喀麦隆在内的撒哈拉以南非洲地区皮肤结核病的文献有限,这凸显了需要报告病例以提高理解.
- 皮肤结核病的多态性往往导致诊断不足,需要提高医疗保健专业人员的意识.
研究的目的:
- 描述喀麦隆艾滋病毒阴性患者皮肤结核病的临床表现和结果.
- 为在撒哈拉以南非洲地区对皮肤结核病的稀缺文献做出贡献.
- 强调在慢性,耐治疗的皮肤病变中考虑皮肤结核病的重要性.
主要方法:
- 一个回顾性案例系列的十名艾滋病毒阴性患者诊断出皮肤结核病在2018年和2022年间在喀麦隆.
- 通过组织学和/或实验室测试来确认诊断.
- 对患者人口统计,临床形式和治疗反应的分析.
主要成果:
- 该研究包括10名HIV阴性患者,平均年龄为35.7岁 (8-72岁),M/F性别比为1.5.
- 确定的临床形式包括皮病 (3),乳头结核病 (2),肺结核病 (2),肺结核病 (1),狼病 (1) 和扩散性结核病 (1).
- 所有患者在用抗结核药物治疗后都表现出良好的临床进展.
结论:
- 皮肤结核病表现出不同的临床表现,强调其多态性质.
- 尽管皮肤结核病很罕见,但在对标准治疗无反应的慢性皮肤病变的差异诊断中,应考虑皮肤结核病.
- 及时诊断和治疗皮肤结核病导致患者的积极结果.
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