从1955年到2022年,中国的白病流行病学在变化
Zengliang Wang1, Ke Li2, Yuanhua Liu3,4
1Department of Epidemiology, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China.
Infectious diseases of poverty
|March 3, 2025
概括
70多年来,中国的白病已经显著下降,但在南方地区仍然令人担忧. 气候和社会经济因素影响传播,需要有针对性的预防,特别是在极端天气事件期间.
科学领域:
- 流行病学 流行病学
- 动物传播疾病 动物传播疾病
- 公共卫生 公共卫生
背景情况:
- 由于Leptospira细菌引起的全球公共卫生问题 - - 牛皮病 - - 自1955年以来,在中国已成为一种必须报告的疾病.
- 在中国,白病的流行病学模式已经在近七十年的时间里演变.
研究的目的:
- 描述从1955年到2022年中国白病的空间,时间和人口统计模式.
- 探索影响莱普托斯皮罗斯感染风险的因素.
主要方法:
- 分析国家监控数据 (1955-2022年) 使用波段时间序列,全球莫兰的I,和时空扫描统计数据.
- 贝叶斯空间时空建模用于识别白病发生的风险因素.
主要成果:
- 报告有超过2500万例病例,其中91%来自7月至10月. 发病率在20世纪60年代至80年代达到顶峰,然后从2005年至2022年稳定在低水平 (0.07/100,000).
- 病例主要发生在中国南部 (>99%),随着时间的推移,空间聚类的增加.
- 确定了关键的风险因素:年平均降水量,人均国内生产总值和农业机械功率.
结论:
- 中国的白病发病率有所下降,但仍存在南北差异,南方地区仍然面临高风险.
- 气候和社会经济因素对疾病模式有着复杂的影响.
- 有针对性的预防至关重要,特别是在易受暴雨和洪水影响的地区,以防止潜在的复苏.
更多相关视频
14:49Application of CRISPR Interference CRISPRi for Gene Silencing in Pathogenic Species of Leptospira
Published on: August 14, 2021
5.0K
11:50High-throughput Parallel Sequencing to Measure Fitness of Leptospira interrogans Transposon Insertion Mutants During Golden Syrian Hamster Infection
Published on: December 18, 2017
8.8K
相关概念视频
01:18Steps in Outbreak Investigation
102
In the ever-evolving field of public health, statistical analysis serves as a cornerstone for understanding and managing disease outbreaks. By leveraging various statistical tools, health professionals can predict potential outbreaks, analyze ongoing situations, and devise effective responses to mitigate impact. For that to happen, there are a few possible stages of the analysis:
102
00:36Viral Mutations
32.1K
A mutation is a change in the sequence of bases of DNA or RNA in a genome. Some mutations occur during replication of the genome due to errors made by the polymerase enzymes that replicate DNA or RNA. Unlike DNA polymerase, RNA polymerase is prone to errors because it is not capable of “proofreading” its work. Viruses with RNA-based genomes, like HIV, therefore accrue mutations faster than viruses with DNA-based genomes. Because mutation and recombination provide the raw material...
32.1K
00:57Viral Recombination
23.2K
Cells are sometimes infected by more than one virus at once. When two viruses disassemble to expose their genomes for replication in the same cell, similar regions of their genomes can pair together and exchange sequences in a process called recombination. Alternatively, viruses with segmented genomes can swap segments in a process called reassortment.
23.2K