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Echocardiographic Measurement of Right Ventricular Diastolic Parameters in Mouse

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右心室大小和功能的回声心脏学参数与持久左心室辅助器件植入后与右心力衰竭相关 - 一个系统性审查和元分析

Jia Cheng Kevyn Chai^1,2, Jia Le Chew¹, Anjalee Amarasekera^3,4

¹Department of Cardiology, Blacktown Hospital, Western Sydney Local Health District, Blacktown, New South Wales, Australia.

Echocardiography (Mount Kisco, N.Y.)

|March 4, 2025

概括

右心室 (RV) 衰竭是长期左心室辅助装置 (D-LVAD) 植入后的常见并发症. 响应心脏图像参数如TAPSE和RVEDD显示出预测这些患者的RV衰竭的潜力.

科学领域:

心脏病学心脏病学
医疗成像医学成像
心血管外科心血管外科

背景情况:

晚期发病的右心室衰竭是耐用左心室辅助装置 (D-LVAD) 植入后的一个已知的并发症.
胸外心声学 (TTE) 是监测RV状态的主要成像工具,但由于设备效应,解释变得复杂.
缺乏对D-LVAD患者TTE解释的具体指导方针,阻碍了对VR大小和功能的准确评估.

研究的目的:

评估TTE参数的诊断和预后效用,以检测D-LVAD后晚期发作的RV故障.
评估D-LVAD植入如何影响RV大小和通过TTE测量的缩功能.
确定特定的TTE指标,可以预测RV故障的发展.

主要方法:

在医学数据库中对2003年1月至2023年8月期间发表的研究进行了系统的文献搜索.
对9项研究 (627名患者) 和3项研究 (175名患者) 的元分析评估了各种结构和功能TTE参数.
对D-LVAD患者的TTE参数与世界心声协会 (WASE) 参考值进行比较.

主要成果:

与WASE规范相比,患有D-LVAD的患者表现出基线RV扩张 (RVEDD) 和缩功能降低 (TAPSE,RVFAC,RVEF).
三 annular 平面缩外流 (TAPSE) 与没有 RV 失效积极相关.
RV终端透析直径 (RVEDD) 与没有RV失败有负相关性,这表明与RV失败的发展有联系.

结论:

患有D-LVAD的患者通常存在VR扩张和缩功能受损.
TAPSE和RVEDD与RV故障发展有显著的关联,表明它们作为预后标记物的潜力.
需要进行进一步的研究,以确定用于VR评估的特定植入后TTE参考值.

关键词:

在RVS.分数面积的变化.心脏衰竭是因为心脏衰竭.非侵入性心脏成像图像检查右心室的大小右心室大小跨胸腔心脏回声学 (Transthoracic Echocardiography) 是一种心脏回声学.

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