压力对工作记忆相关的前额处理的影响:fNIRS研究
Christoph Felix Geissler1, Christian Frings1,2, Gregor Domes1,3
1Institute for Cognitive & Affective Neuroscience, Trier University, Trier, Germany.
Stress (Amsterdam, Netherlands)
|March 4, 2025
概括
急性压力可能会通过影响前额叶大脑活动来损害工作记忆,这可能与皮质醇水平有关. 需要进一步的研究才能充分理解这种随时间推移的关系.
科学领域:
- 神经科学是一个神经科学.
- 心理学 心理学 心理学
- 内分泌学 在内分泌学.
背景情况:
- 急性压力会使行为转向自动反应,对工作记忆等执行功能产生负面影响.
- 工作记忆在压力后的10分钟和25分钟内特别脆弱,与增加的诺亚上腺素和皮质醇相吻合.
- 较高的压力激素水平可能会使前额叶区域失活,这对工作记忆至关重要.
研究的目的:
- 为了研究急性压力,压力激素,神经活动和工作记忆在时间上的关系.
- 检查社会评估的冷压器测试对前额活动和压力标志物的影响.
主要方法:
- 功能近红外光谱学 (fNIRS) 在n-back任务中测量了前额活动.
- Salivary皮质醇和α-amylase (诺亚地腺素相关物) 经常被测量.
- 参与者包括一个压力组 (n=28) 和一个控制组 (n=28).
主要成果:
- 在急性压力后14分钟,唾液皮质醇水平增加.
- 没有观察到压力对唾液α-氨酶或工作记忆表现的显著影响.
- 与控制组相比,压力组的前额活动与背后任务相关的前额活动下降的趋势更大.
结论:
- 结果表明,急性压力对前额前部工作记忆处理有潜在的负面影响.
- 皮质醇可能会调解急性压力对与工作记忆相关的神经活动的观察到的影响.
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