需要交换输血的高白血症作为晚期发病听力损失的危险因素
Susan Wiley1, Vivian Kaul2, Oliver F Adunka3,4
1Cincinnati Children's Hospital Medical Center/University of Cincinnati, Cincinnati, OH.
概括
需要交换输血的高白血是儿童听力损失的危险因素. 患有这种疾病的婴儿应接受自动听力脑干反应查和持续监测,以获得最佳结果.
科学领域:
- 儿科听力学 儿科听力学
- 新生儿护理 新生儿护理
- 基于证据的医学基于证据的医学.
背景情况:
- 婴儿听力联合委员会 (JCIH) 之前已经确定了需要交换输血的高白血症是儿童听力损失的危险因素.
- 本审查批判性地审查了支持JCIH建议的证据.
研究的目的:
- 评估证据的强度,将需要交换输血的高白血症与儿童听力损失联系起来.
- 根据临床实践指南,为高危婴儿进行听力查和监测提供信息.
主要方法:
- 使用PubMed进行了全面的文献搜索,关键词是"高白血症"和"听力损失".
- 确定了77篇原始论文,其中44篇经过全面审查,21篇被评为证据质量.
- 建议是基于分级证据和专家的共识.
主要成果:
- 中等水平的证据支持需要交换输血的高 bilirubinemia 作为婴儿和幼儿听力值升高的危险因素.
- 建议对这种婴儿群体进行自动听力脑干反应查.
- 这些干预措施的净收益是中等到实质性的.
结论:
- 对听力,言语和语言里程碑的密切监测对于需要交换输血的高 bilirubinemia 婴儿至关重要,即使他们通过新生儿听力查.
- 早期发现和干预可以改善发育结果.
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