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Updated: Jun 6, 2026

An Orthotopic Bladder Tumor Model and the Evaluation of Intravesical saRNA Treatment
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膀癌中单细胞RNA测序和空间转录组分析:当前状况和未来前景

Kentaro Yoshihara1,2, Kagenori Ito1, Takahiro Kimura1

  • 1Department of Urology, The Jikei University School of Medicine, Tokyo, Japan.

Bladder cancer (Amsterdam, Netherlands)
|March 4, 2025
PubMed
概括

单细胞RNA测序和空间转录组学揭示了膀癌亚型和治疗抵抗机制. 这些先进的技术为个性化膀癌疗法和生物标志物发现提供了新的途径.

关键词:
膀癌:膀癌是一种癌症.细胞与细胞的相互作用.一个单细胞RNA测序.空间转录学 空间转录学瘤微环境是一个微环境.

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lncRNA - Long Non-coding RNAs

In humans, more than 80% of the genome gets transcribed. However, only around 2% of the genome codes for proteins. The remaining part produces non-coding RNAs which includes ribosomal RNAs, transfer RNAs, telomerase RNAs, and regulatory RNAs, among other types. A large number of regulatory non-coding RNAs have been classified into two groups depending upon their length – small non-coding RNAs, such as microRNA, which are less than 200 nucleotides in length, and long non-coding RNA (lncRNA)...