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Updated: May 24, 2025

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单细胞RNAseq揭示了肝脏内胆管癌恶性细胞中不良的代谢转录程序

Christophe Desterke1, Raquel Francés2, Claudia Monge3

  • 1Faculté de Médecine du Kremlin Bicêtre, Université Paris-Saclay, INSERM UMRS-1310, Le Kremlin-Bicêtre, France.

Biochemistry and biophysics reports
|March 4, 2025
PubMed
概括

代谢基因表达特征预测肝脏内胆管癌 (ICA),一种侵袭性肝癌的预后不佳. 这种特征与增殖性子类相关,并且独立于瘤阶段或纤维化.

关键词:
酵素酶是一种酶.在肝脏内发生的胆管癌,胆管癌.凯格·梅塔斯科尔 (Kegg Metascore) 获得了一个比分.肝癌是一种肝癌.代谢得分 (Metabolic Score) 是指代谢得分 (Metabolic Score) 是指代谢得分 (Metabolic Score).一个单细胞RNA测序.

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Multicellular organisms contain a variety of structurally and functionally distinct cell types, but the DNA in all the cells originated from the same parent cells. The differences in the cells can be attributed to the differential gene expression. Liver cells, whose functions include detoxification of blood, production of bile to metabolize fats, and synthesis of proteins essential for metabolism, must express a specific set of genes to perform their functions. Gene expression also varies with...
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