生物活性小化合物有效抑制ChREBP过度表达以治疗NAFLD和T2DM:一种计算药物开发方法

Hiron Saraj Devnath1, Maisha Maliha Medha1, Md Naharul Islam1

  • 1Pharmacy Discipline, Khulna University, Khulna, 9208, Bangladesh.

Heliyon
|March 4, 2025
PubMed
概括

研究人员确定了针对碳水化合物反应元素结合蛋白 (ChREBP) 的天然化合物,用于治疗非酒精性脂肪肝疾病 (NAFLD) 和II型糖尿病 (T2DM). 五种植物化学物质显示出作为有效药物候选物的强大潜力.

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