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在 orofacial 疼痛条件中的生物标志物:叙述性审查

Mervin Harris¹, Saranya Sreekumar^1,2, Bindhu Paul³

¹Department of Prosthodontics, Amrita School of Dentistry, Amrita Institute of Medical Sciences and Research Centre, Amrita Vishwa Vidyapeetham Kochi, Kerala, 682041, India.

Journal of oral biology and craniofacial research

|March 4, 2025

概括

分子和遗传生物标志物显示出诊断和治疗像TMD和偏头痛这样的口腔疼痛状况的前景. 需要进一步的研究来克服挑战,并将发现转化为临床实践.

科学领域:

生物医学研究的研究.
分子生物学分子生物学
遗传学是一个遗传学.

背景情况:

面部或面部疼痛症状显著影响生活质量.
了解病理生理学正在进步,对生物标志物的兴趣越来越大.
生物标志物对于诊断,监测和治疗口腔面部疼痛至关重要.

研究的目的:

提供关于 orofacial 疼痛生物标志物的当前研究的全面概述.
为了识别各种或面部疼痛条件中的关键生物标志物.
突出生物标志物研究的挑战和未来方向.

主要方法:

对现有文献进行范围审查.
对分子和遗传生物标志物研究的分析.
识别与炎症,神经活动和组织退化相关的生物标志物.

主要成果:

确定了针对面部或面部疼痛条件的常见和特定生物标志物.
突出了生物标志物的潜力,以实现个性化治疗策略.
指出了一些挑战,包括研究设计的异质性,小样本大小和缺乏纵向数据.

结论:

生物标志物具有显著的潜力,可以改善面部疼痛的诊断和治疗.
解决研究挑战对于临床翻译至关重要.
需要进一步的研究来开发有效的,个性化的治疗方法来治疗面部疼痛.

关键词:

生物标记物生物标记物细胞因子 (cytokines) 是一种细胞因子.偏头痛疾病偏头痛疾病短关节疾病短关节疾病三胞胎神经疼痛三胞胎神经疼痛

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