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Updated: May 24, 2025

Using Next Generation Sequencing to Identify Mutations Associated with Repair of a CAS9-induced Double Strand Break Near the CD4 Promoter
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评估DNA修复缺陷的Listeria monocytogenes中的突变积累:在疫情分析中对cgMLST集群值的影响

Astrid Füszl1, Ariane Pietzka1, Patrick Hyden2

  • 1National Reference Centre/Laboratory for Listeriosis, Austrian Agency for Health and Food Safety (AGES), Vienna/Graz, Austria.

Frontiers in cellular and infection microbiology
|March 4, 2025
PubMed
概括

在Listeria monocytogenes中具有DNA修复缺陷的高突变率可能会错误地分类爆发菌株. 调整核心基因组多部位序列类型化 (cgMLST) 值可能会提高Listeria爆发检测的准确性.

关键词:
李斯特里亚单细胞原生菌 (Listeria monocytogenes) 是一种一个等位基因的值.核心基因组多部位序列的类型化.李斯特菌病是指李斯特菌病的发生.突变率的变化率是如何发生的疫情爆发的检测和检测.

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