在老年和年轻的男性和女性中,短期禁食后的宏观营养素利用,试点研究
San Wang1, Rita Tsay1, Danya Zhang2
1Massachusetts Institute of Technology.
Research square
|March 4, 2025
概括
老年人在禁食期间调动和氧化宏观营养素,与年轻人相似. 36小时的禁食显著影响了整体新陈代谢,年龄和性别的影响很小.
科学领域:
- 老年学是指老年学的学科.
- 人类的新陈代谢.
- 营养科学 营养科学
背景情况:
- 衰老与代谢,激素和身体组成的变化有关.
- 老年人更容易受到非自愿的禁食的影响.
- 关于老年人禁食期间的宏观营养素利用情况的数据有限.
研究的目的:
- 在禁食期间调动和氧化宏营养素的年龄相关差异的调查.
- 为了测试老年人与年轻人不同的基质利用动力学,这一假设.
主要方法:
- 试点研究涉及四组:年长/年轻男性/女性.
- 通过双能X射线吸收计 (DEXA) 评估的身体组成.
- 稳定同位素标记仪和间接热量计用于在12小时和36小时的禁食期间测量基质的外观和氧化率.
主要成果:
- 年龄较大的参与者身体脂肪的百分比更高.
- 呼吸交换比率 (RER) 随着禁食时间的延长而下降.
- 在大多数代谢参数中,年龄不是一个重要的因素,除了糖醇和氨酸的比率.
结论:
- 老年人禁食期间的代谢切换与年轻人的代谢切换类似.
- 36小时禁食对宏观营养素代谢的影响很大,超过了年龄和性别差异.
- 研究结果表明,年龄组之间的禁食适应程度相似.
关键词:
衰老的衰老 衰老的衰老身体构成 身体组成双能量X射线吸收度计.禁食禁食是一種禁食.脂肪溶解是指脂质分解的过程.呼吸系数 呼吸系数休息的能源支出 休息的能源支出稳定同位素的标记物.基质氧化过程中的基质氧化.基质出现的速度.更多相关视频
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