制定诊断检查清单,以识别功能性认知障碍与其他神经认知障碍之间的差异
Verónica Cabreira1, Jane Alty2, Sonja Antic3
1Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.
BMJ neurology open
|March 4, 2025
概括
一个新的临床检查清单有效地将功能性认知障碍 (FCD) 与其他神经认知障碍区分开来. 这个工具有助于诊断FCD,改善患者的护理.
科学领域:
- 神经科学是一个神经科学.
- 临床心理学 临床心理学
- 精神病学是一个精神病学.
背景情况:
- 功能性认知障碍 (FCD) 由于症状与其他神经认知障碍重叠而带来诊断挑战.
- 目前生物标志物的准确性有限,因此需要改进FCD的诊断工具.
- 区分FCD与神经退行性疾病对于适当的患者管理至关重要.
研究的目的:
- 开发和验证用于识别功能性认知障碍 (FCD) 的新型诊断检查清单.
- 创建一个工具,可以将FCD与其他神经认知障碍区分开来.
- 评估开发的检查清单的区分性准确性.
主要方法:
- 一种混合方法的方法,结合文献综述,与45名国际临床医生进行的德尔菲研究,以及一项试点歧视性准确性研究.
- 制定11项检查清单,然后通过删除多余项目的方式创建更简短的7项版本.
- 使用克朗巴赫的α和最佳切断值得分来评估内部有效性,通过239名患者的接收器运行特征曲线分析确定.
主要成果:
- 完整的11项检查清单和简短的7项检查清单都显示出优异的分辨准确性 (AUC分别为0.97和0.96).
- 检查清单在识别FCD时实现了高特异性 (97%) 和积极的预测值 (91%).
- 在FCD和其他神经认知障碍组之间观察到检查清单得分的显著差异 (p<0.001),具有良好的内部有效性 (>0.80).
结论:
- 一个简短的临床检查清单显示,作为区分FCD和神经退行性疾病的补充工具,它是有前途的.
- 开发的检查清单提供了一个快速而准确的方法来支持FCD诊断.
- 建议在多种不同人群中进行进一步的大规模,前性验证.
相关概念视频
Intellectual Disability
34
Intellectual disability (ID) is a neurodevelopmental condition characterized by deficits in intellectual and adaptive functioning that manifest during the developmental period. This condition encompasses challenges in reasoning, memory, problem-solving, and learning, accompanied by impairments in everyday life skills, such as communication, self-care, and social interactions. Intellectual disability affects approximately 1% of the population in the United States, impacting an estimated 5...
34
Diagnostic and Statistical Manual of Mental Disorders (DSM)
35
The Diagnostic and Statistical Manual of Mental Disorders (DSM) serves as the primary classification system for mental health disorders, providing standardized diagnostic criteria for clinicians and researchers. First published by the American Psychiatric Association (APA) in 1952, the DSM has undergone several revisions to reflect evolving psychiatric understanding. The fifth edition, DSM-5, released in 2013, introduced key updates that expanded diagnostic categories and modified diagnostic...
35
Attention-Deficit/Hyperactivity Disorder
34
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
34
Cognitive Development During Adulthood
43
Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
43
Dementia
87
Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual....
The progression of dementia is generally gradual....
87
Formulating and Validating Nursing Diagnosis I
2.5K
A nursing diagnosis is written when the nurse recognizes a cluster of essential patient data indicating health problems treated with independent nursing interventions. The standardized terminologies of a nursing diagnosis help nurses identify and treat patients' problems. Every electronic health record that uses nursing diagnosis must employ standard diagnostic terminology. Developing an efficient, individualized care plan begins with accurate nursing diagnoses.
There are thirteen domains...
There are thirteen domains...
2.5K


