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Updated: May 24, 2025

Three-Dimensional Bone Extracellular Matrix Model for Osteosarcoma
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Published on: April 12, 2019

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METTL3/TGF-β1信号轴通过通过m6A修改诱导MSC分化为CAFs来促进骨髓瘤的进展

Jin Qi1,2, Sihang Liu1, Baomin Wu3

  • 1Department of Orthopedics, The First Affiliated Hospital of Wannan Medical College (Yijishan Hospital of Wannan Medical College), Wuhu 241001, Anhui Province, China.

Journal of bone oncology
|March 4, 2025
PubMed
概括

METTL3/TGF-β1信号轴通过促进中酶体干细胞分化成与癌症相关的纤维细胞驱动骨髓瘤的进展. 这个轴是晚期骨髓瘤的潜在治疗点.

关键词:
与癌症相关的纤维细胞.介质细胞干细胞 介质细胞干细胞类似于甲基转移酶的3骨质肉瘤骨质肉瘤是什么转化生长因子-β1的转化.

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Studying TGF-β Signaling and TGF-β-induced Epithelial-to-mesenchymal Transition in Breast Cancer and Normal Cells06:54

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