Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

MicroRNAs01:22

MicroRNAs

21.1K
MicroRNA (miRNA) are short, regulatory RNA transcribed from introns—non-coding regions of a gene—or intergenic regions—stretches of DNA present between genes. Several processing steps are required to form biologically active, mature miRNA. The initial transcript, called primary miRNA (pri-mRNA), base-pairs with itself forming a stem-loop structure. Within the nucleus, an endonuclease enzyme, called Drosha, shortens the stem-loop structure into hairpin-shaped pre-miRNA. After...
21.1K
Cognitive Enhancers: Cholinesterase Inhibitors and NMDA Receptor Antagonists01:30

Cognitive Enhancers: Cholinesterase Inhibitors and NMDA Receptor Antagonists

92
Cognitive enhancers, also known as "smart drugs," are substances used to enhance memory, mental alertness, and concentration. These can be natural or synthetic and improve cognition in conditions like Alzheimer's disease (AD) and other neurodegenerative diseases. Some common examples include caffeine, amphetamines, methylphenidate, modafinil, arecoline, donepezil, vortioxetine, and piracetam. These enhancers work on the principle of synaptic plasticity and altered circuit function.
92

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Time-Restricted Eating and Intermittent Fasting: Trendy or Trusty?

The Journal of nutrition·2026
Same author

Extracellular Vesicle-like Associated microRNAs in Monofloral Honeys: Molecular Characterization and Functional Pathways.

International journal of molecular sciences·2026
Same author

Zinc Complexation Overcomes the Context-Dependent Metabolic Effects of Curcumin in TNBC: Molecular Insights from TLR4/MD-2 Targeting.

Current issues in molecular biology·2026
Same author

Effects of High-Intensity Interval Training with Blood Flow Restriction Versus Normobaric Hypoxia on Physiological Parameters in Apparently Healthy Young Men.

Sports (Basel, Switzerland)·2026
Same author

Comparison of Repetition-Based Progressive-Overload Strategies in Resistance Training: Rest-Pause Versus Drop Sets.

Scandinavian journal of medicine & science in sports·2026
Same author

Exploring the Influence of Oral-Proximal Gastric in Vitro Digestion on Estimated Glycemic Index and Bioaccessibility of Bioactive Phenolic Compounds of Wheat-Based Baked Products.

Food science & nutrition·2026

相关实验视频

Updated: May 24, 2025

Tissue-specific miRNA Expression Profiling in Mouse Heart Sections Using In Situ Hybridization
08:22

Tissue-specific miRNA Expression Profiling in Mouse Heart Sections Using In Situ Hybridization

Published on: September 15, 2018

8.1K

性饮食和microRNAs:专注于认知功能

Diana Marisol Abrego-Guandique1, Erika Cione2,3, Maria Cristina Caroleo1,3

  • 1Department of Health Sciences, University of Magna Graecia Catanzaro, Catanzaro, Italy.

Frontiers in nutrition
|March 4, 2025
PubMed
概括

性饮食 (KD) 可能通过调节microRNAs (miRNAs) 来改善认知功能,microRNAs与阿尔茨海默氏症等神经退行性疾病有关. 本综述探讨了KD在增强认知和miRNAs保护作用中的作用.

关键词:
生物标志物生物标志物认知功能 认知功能基因饮食是什么 基因饮食是什么体是指体中的体.微RNAs 是一个微型RNA.

更多相关视频

Characterization of Functionally Associated miRNAs in Glioblastoma and their Engineering into Artificial Clusters for Gene Therapy
09:40

Characterization of Functionally Associated miRNAs in Glioblastoma and their Engineering into Artificial Clusters for Gene Therapy

Published on: October 4, 2019

5.6K
Stereotactic Injection of MicroRNA-expressing Lentiviruses to the Mouse Hippocampus CA1 Region and Assessment of the Behavioral Outcome
09:06

Stereotactic Injection of MicroRNA-expressing Lentiviruses to the Mouse Hippocampus CA1 Region and Assessment of the Behavioral Outcome

Published on: June 10, 2013

22.8K

相关实验视频

Last Updated: May 24, 2025

Tissue-specific miRNA Expression Profiling in Mouse Heart Sections Using In Situ Hybridization
08:22

Tissue-specific miRNA Expression Profiling in Mouse Heart Sections Using In Situ Hybridization

Published on: September 15, 2018

8.1K
Characterization of Functionally Associated miRNAs in Glioblastoma and their Engineering into Artificial Clusters for Gene Therapy
09:40

Characterization of Functionally Associated miRNAs in Glioblastoma and their Engineering into Artificial Clusters for Gene Therapy

Published on: October 4, 2019

5.6K
Stereotactic Injection of MicroRNA-expressing Lentiviruses to the Mouse Hippocampus CA1 Region and Assessment of the Behavioral Outcome
09:06

Stereotactic Injection of MicroRNA-expressing Lentiviruses to the Mouse Hippocampus CA1 Region and Assessment of the Behavioral Outcome

Published on: June 10, 2013

22.8K

科学领域:

  • 神经科学是一个神经科学.
  • 分子生物学分子生物学
  • 饮食科学 饮食科学

背景情况:

  • 认知依赖于记忆,并受到微RNA (miRNA) 的影响.
  • 微RNA与神经发育和认知功能有关.
  • 在影响认知的神经退行性疾病中观察到失调的miRNAs.

研究的目的:

  • 审查miRNAs在神经发育和认知中的功能.
  • 探索性饮食 (KD) 对人类认知功能的影响.
  • 突出miRNAs在神经疾病中的神经保护作用.

主要方法:

  • 关于性饮食,miRNAs和认知的研究的文献综述.
  • 对研究KD效应的人类和动物模型的分析.
  • 综合目前关于kd的miRNA调制的研究.

主要成果:

  • 积累的证据表明,KD有利于神经退行性疾病影响认知.
  • 肯德基有可能调节大脑中的miRNAs.
  • miRNAs在维持认知健康方面发挥着至关重要的作用.

结论:

  • 素饮食显示了增强认知功能的前景.
  • 微RNA是认知过程和神经健康的关键调节者.
  • 对KD和miRNA相互作用的进一步研究可能会产生治疗认知衰退的治疗策略.