通过结合从-18氧葡萄糖位电子发射断层扫描/计算机断层扫描成像中获得的半定量和视觉发现,改善感染性内心炎的诊断
Özge Vural Topuz1, Furkan Gür1, Burcu Esen Akkaş1
1Department of Nuclear Medicine, University of Health Sciences, Başakşehir Cam and Sakura City Hospital, Istanbul, Türkiye.
-18氧葡萄糖正子发射断层扫描/计算机断层扫描 (F-18 FDG PET/CT) 有效地诊断出感染性内心炎 (IE). 骨髓增加的FDG吸收与IE密切相关,提高了诊断准确度.
科学领域:
- 核医学就是核医学.
- 放射学 放射学是一门学科.
- 传染性疾病 传染性疾病
背景情况:
- 感染性内心炎 (IE) 的诊断可能具有挑战性.
- F-18 FDG PET/CT 越来越多地用于诊断各种疾病.
- 和骨髓吸收在IE诊断中的作用需要进一步评估.
研究的目的:
- 为了评估IE诊断的视觉和半定量F-18 FDG PET/CT输出.
- 为了确定或骨髓FDG吸收增加是否有助于IE诊断.
主要方法:
- 对因疑似IE而接受F-18 FDG PET/CT的患者的回顾性分析.
- 根据诊断标准对IE阳性和对照组进行分类.
- 对病变,肝脏,脏和骨髓的分析标准化吸收值 (SUV) 和衍生比率.
主要成果:
- 在IE和对照组之间,损伤SUV,吸收得分,脏和骨髓超能代谢的显著差异.
- 高吸收得分实现了IE的85.42%灵敏度和84.06%准确度.
- 损伤SUVmax>3.5显示高特异性 (95.24%) 和积极的预测值 (96.77%).
结论:
- 视觉F-18 FDG吸收评估和SUV> 3.5准确区分IE患者.
- 骨髓增加的FDG吸收是与IE相关的重要指标.
- F-18 FDG PET/CT为感染性内心炎提供了宝贵的诊断见解.
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