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Updated: May 24, 2025

Preparation of Stable Bicyclic Aziridinium Ions and Their Ring-Opening for the Synthesis of Azaheterocycles
11:45

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Published on: August 22, 2018

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一种基于氨酸的合成方法,用于获取未充分利用的aza-indole类似物

Evan Savelson1, Katarina A Selewski1, Jetze J Tepe1

  • 1Department of Chemistry, University of Virginia, 409 McCormick Rd, Charlottesville, VA, 22904, USA.

Chemistry (Weinheim an der Bergstrasse, Germany)
|March 4, 2025
PubMed
概括

研究人员开发了一种新的合成途径,以访问罕见的aza-indole支架,特别是pyrazolopyridazines. 这种方法增强了药物发现,通过提供对新型化合物的访问,这些化合物具有比传统的英多尔更好的特性.

关键词:
亚萨 - 印度尔斯 (Aza-indoles) 是一个循环添加 循环添加异循环是指异循环的.这些是Pyrazolopyridazines.泰特拉辛 (tetrazine) 是一种四氨酸.

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