PMEPA1NEDD4L,Wnt/β-catenin

Shanshan Hu1, Xinfang Gao1, Yan Zhu1

  • 1Department of Hematology, Jinhua People's Hospital, Jinhua City, Zhejiang Province, 321000, China.

概括

前列腺跨膜雄激素诱导蛋白1 (PMEPA1) 通过结合神经前体细胞表达的下调发育基因4L (NEDD4L) 来抑制Wnt/β-catenin信号传递,从而抑制多发性骨髓瘤 (MM) 的进展,从而提供潜在的治疗标.

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