儿童慢性病的主要原因的发生率 使用电子健康记录驱动的可计算表型
Jonathan M Beus1, Katie Liu1, Adrianna Westbrook1
1Emory University and Children's Healthcare of Atlanta, Atlanta, Georgia, United States.
Kidney360
|March 4, 2025
概括
电子健康记录算法准确地确定了儿科慢性病 (CKD) 病例. 这些发现为儿童CKD提供了关键的发病率估计,突出了其患病率.
科学领域:
- 儿科脏病学 儿科脏病学
- 流行病学 流行病学
- 医疗信息学 医疗信息学
背景情况:
- 儿童慢性病 (CKD) 发病率数据有限.
- 基于电子健康记录 (EHR) 的算法 (e-phenotypes) 被开发来解决这个差距.
- 该研究的重点是估计五个主要的儿科CKD病因的发病率.
研究的目的:
- 开发和验证基于EHR的e-表型,用于识别儿科CKD病例.
- 估计儿童慢性病的五大主要原因的发生率.
- 评估开发的e-表型的性能.
主要方法:
- 使用标准化临床术语和特定的包含/排除标准,创建了E-表型.
- 在10年内 (2014-2023年) 从亚特兰大MSA的单一儿科脏病提供者中确定了病例.
- 对1000名儿科患者的算法性能进行了评估,使用人口数据计算出发病率.
主要成果:
- 这些e-表型表现出高性能:灵敏度 (0.83-0.95),特异性 (0.96-1.00),PPV (0.81-1.00) 和NPV (0.98-1.00).
- 总共有6814例儿科慢性病例被确定.
- 这些慢性病的总年发病率为每10万名儿童中有47.07,其中脏和尿路的先天性异常 (CAKUT) 是最常见的.
结论:
- 儿科CKD的情况比以前估计的更为常见.
- 开发的e-表型是CKD研究的宝贵工具,但需要外部验证.
- 这些算法可以促进对儿童CKD决定因素,管理和结果的进一步研究.
相关概念视频
Nephrons
2.0K
The kidneys are intricate organs with millions of working units known as nephrons. Each nephron features two major structures: the renal corpuscle, which facilitates blood plasma filtration, and the renal tubule, which handles the glomerular filtrate. Blood supply is directly linked to the nephrons. The renal corpuscle consists of the glomerulus, a capillary network, and the Bowman's capsule, a double-walled epithelial structure that encases the glomerulus. The filtering of blood plasma...
2.0K
Documentation of Nursing Diagnosis
1.2K
The nurse documents nursing diagnoses and enters them into the patient record. The identified patient's nursing diagnosis is either written out with a plan of care or entered into the electronic health record.
In some settings, data-driven computerized decision support systems are in place, allowing for more accurate nursing diagnoses. The database within one of these systems includes diagnostic labels defining characteristics, activities, and indicators for nursing. A nurse enters...
In some settings, data-driven computerized decision support systems are in place, allowing for more accurate nursing diagnoses. The database within one of these systems includes diagnostic labels defining characteristics, activities, and indicators for nursing. A nurse enters...
1.2K
Factors Affecting Renal Clearance: Renal Impairment
47
Renal dysfunction significantly impairs the renal clearance of drugs, leading to potential complications in drug therapy. Renal failure, which can be caused by various factors, poses a significant challenge in the elimination of drugs from the body.
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...
47
Pedigree Analysis
83.7K
Overview
83.7K
Methods of Documentation VII: EMR
823
Electronic Medical Records (EMRs) primarily center around electronically documenting patients' health information within a single healthcare organization or practice. They contain essential clinical data related to a patient's medical history, diagnoses, medications, treatment plans, lab results, and other pertinent information relevant to the specific encounter or episode of care. EMRs are designed to streamline documentation and workflow processes within individual healthcare...
823


