在多发性肌痛性风湿症中,抑郁症的更高率与身体功能不佳密切相关
Jessica L Leung, Natalie Deeble1, Victor Yang1
1From the Department of Rheumatology, Austin Health.
概括
抑郁症影响多发性肌痛风湿症 (PMR) 患者的高达25%,与身体功能限制密切相关. 解决抑郁症对于管理PMR结果至关重要.
科学领域:
- 类风湿病学 类风湿病学
- 精神病学是一个精神病学.
- 流行病学 流行病学
背景情况:
- 多发性肌痛性风湿症 (PMR) 是一种炎症状况,与患者的重大负担有关.
- 抑郁症是慢性疾病中常见的并发症,但其在PMR中的患病率和风险因素尚未得到充分确定.
研究的目的:
- 为了确定患有多发性肌痛风湿症 (PMR) 的患者中抑郁症的患病率.
- 与对照组相比,确定与PMR患者抑郁症相关的风险因素.
主要方法:
- 一项纵向队列研究,将新诊断的PMR患者与匹配的对照进行比较.
- 在基线和21个月使用医院焦虑和抑郁量表 (HADS) 和SF-36心理健康 (MH) 量表进行情绪评估.
- 数据收集包括疾病活动,疼痛,功能状态和药物剂量.
主要成果:
- 在PMR患者 (22.2-25.0%) 和对照组 (0-3.1%) 中,抑郁症的发病率显著更高.
- 身体功能不佳是抑郁症最强的预测因素 (OR 8.19-13.25).
- 较高的普得尼索隆剂量,疾病活性,疼痛和疲劳也与抑郁相关.
结论:
- 在高达25%的PMR患者中,抑郁症很普遍.
- 身体上的限制在很大程度上导致了PMR的心理负担.
- 针对身体和精神健康的综合护理对于最佳的PMR患者结果至关重要.
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