心血管疾病的教育不平等及其介导因素跨越不同世代:一个前性队列研究
Nana Wang1, Xiaocan Jia1, Zhixing Fan2
1Department of Epidemiology and Biostatistics, College of Public Health, Zhengzhou University, Zhengzhou 450001 Henan, China.
概括
心血管疾病 (CVD) 的教育差异在几代人中持续存在,受教育程度较低的人面临更高的风险. 针对这些群体的健康生活方式和代谢因素可能会减少健康不平等.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 健康的社会决定因素
背景情况:
- 教育不平等与心血管疾病 (CVD),冠心病 (CHD) 和中风的差异有关.
- 对于公共卫生干预措施来说,了解不同出生群体之间的这些不平等至关重要.
研究的目的:
- 评估四代人对心血管疾病,心血管疾病和中风发病率的教育不平等.
- 分析健康的生活方式和代谢因素在这些不平等中扮演的调解角色.
主要方法:
- 对447,227名英国生物库参与者进行的前性队列研究,涉及四个出生世代 (1930年代-1960年代).
- 使用考克斯回归,相对不平等指数 (RII) 和反事实调解分析.
- 评估了教育,心血管疾病,心血管疾病,中风,生活方式因素和代谢健康之间的关联.
主要成果:
- 在心血管疾病发病率方面观察到显著的教育不平等,跨世代教育水平较低的风险增加.
- 对心血管疾病的相对不平等指数 (RII) 从20世纪30年代的1.04增加到20世纪60年代的1.35.
- 健康的生活方式和代谢因素对心血管疾病不平等的比例分别为13.36%-21.72%和30.65%-40.70%.
结论:
- 在心血管疾病发病率方面的教育不平等仍然存在,并且在最近的几代人中可能正在扩大.
- 针对受教育程度较低的人群的健康生活方式和代谢因素的干预措施是必要的,以减少健康差异.
- 研究结果强调了在心血管健康战略中解决社会经济决定因素的重要性.
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