tDCS对改善精神分裂症患者社会认知的内观准确性的潜在延迟积极影响
Linlin Fan1, Emily Bass2, Hans Klein2
1Department of Psychology, Faculty of Social Sciences, University of Macau, Macao SAR, China.
Schizophrenia bulletin
|March 4, 2025
概括
经直流刺激 (tDCS) 可能为精神分裂症患者提供延迟的好处,改善内省准确性 (IA) 和任务性能,特别是在社会认知方面,在重复的会议后.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 神经调节是一种神经调节.
背景情况:
- 内观准确性 (IA) 障碍在精神分裂症中很常见,影响日常功能,并代表治疗目标.
- 右侧面前额叶皮层 (rlPFC) 参与IA,经直流刺激 (tDCS) 显示了改善的潜力.
研究的目的:
- 为了研究tDCS应用于正确的rlPFC在增强精神分裂症患者IA的疗效.
- 探索tDCS对IA和认知表现的潜在顺序和延迟影响.
主要方法:
- 一项随机,双盲,假控制的交叉研究,涉及40名精神分裂症谱系障碍患者.
- 患者接受了两次tDCS会议 (活跃和虚假),目标是右侧rlPFC,大约隔一周.
- 通过执行功能和情绪识别任务在刺激后评估IA.
主要成果:
- 总的来说,tDCS没有显著影响表现或IA,除了在积极刺激后对认知任务的信心增加.
- 然而,考虑到顺序效应,接受活性tDCS的组首先显示了认知和社会认知任务性能和社会认知IA的改善.
- 假的第一组没有随着时间的推移显著地改变了性能或IA.
结论:
- 初步证据表明,对正确的rlPFC应用的tDCS可能会延迟对精神分裂症的任务执行和IA的积极影响.
- 这些发现突出了tDCS作为治疗干预措施的潜力,以改善精神分裂症患者的自我意识和认知功能,这需要进一步调查延迟效应.
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