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Updated: May 5, 2026

Exogenous Administration of Microsomes-associated Alpha-synuclein Aggregates to Primary Neurons As a Powerful Cell Model of Fibrils Formation
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Exogenous Administration of Microsomes-associated Alpha-synuclein Aggregates to Primary Neurons As a Powerful Cell Model of Fibrils Formation

Published on: June 26, 2018

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对α-synuclein的自身抗体抑制了它的聚合和细胞毒性

Carmen Noelker1, Florian Seitz1, Annekathrin Sturn1

  • 1Department of Neurology, Philipps-University Marburg, Rudolf-Bultmann Strasse 8, 35033, Marburg, Germany.

Journal of autoimmunity
|March 4, 2025
PubMed
概括

对抗α-synuclein (α-Syn) 的自然存在的自身抗体被分离和特征. 这些自身抗体抑制α-Syn纤维素的形成并逆转其毒性,表明潜在的帕金森氏症.

关键词:
自动抗体是一种自身抗体.静脉内注射的免疫球蛋白是可以使用的.帕金森病的疾病.协同核蛋白是一种同核蛋白.

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