扫描成像的发现与硬质皮相关的神经病变:一个系统的文献综述
Elvina Ingrid1, Mathuja Bavanendrakumar2, Shereen Oon2
1Department of Rheumatology, Western Health, 160 Gordon Street, Footscray, VIC 3011 Australia; Department of Rheumatology, Austin Health, Level 1 North Wing Heidelberg Repatriation Hospital, 300 Waterdale Road, Heidelberg Heights, VIC 3081, Australia; Department of Rheumatology, St Vincent's Hospital Melbourne, 41 Victoria Parade, Fitzroy, VIC 3065 Australia.
Seminars in arthritis and rheumatism
|March 4, 2025
概括
系统性硬化症肌肉病常常被标准测试遗漏. 肌肉成像,特别是MRI,可以检测炎症和缩变化,这表明其在诊断这种疾病中的价值.
科学领域:
- 风湿病学和免疫学
- 肌肉骨成像系统的成像
- 肌肉病理学 肌肉病理学
背景情况:
- 系统性硬化症 (SSc) 直接影响骨肌肉,导致SSc相关肌肉病 (SSc-myopathy),一种免疫媒介的疾病.
- 传统的诊断方法,如手动肌肉测试和肌酸激酶 (CK) 水平,往往对SSc-myopathy不敏感.
研究的目的:
- 评估SSc-肌肉病的各种成像方法的诊断效用.
- 评估成像在检测系统性硬化症患者骨肌异常中的作用.
主要方法:
- 在MEDLINE,Pubmed和EMBASE中进行了系统的文献审查.
- 包括的研究是那些至少有10名SSc患者报告骨肌肉成像结果的研究.
- 使用NHLBI质量评估工具评估偏差风险;数据被描述性地总结.
主要成果:
- 磁共振成像 (MRI) 是最常见的方法,在38-100%的患者中发现异常,包括,缩和脂肪透.
- 影像检测检测到各种肌肉群的变化,但CK水平,临床弱点和影像检测结果之间没有一致的相关性.
- 有限的数据阻止了识别明显的成像模式或与细胞病理学的直接相关性.
结论:
- 肌肉成像有效地识别SSc患者的骨肌肉中的炎症,缩和血管病变.
- 临床评估和成像发现之间的差异突出显示了肌肉成像在查和诊断SSc-myopathy方面的潜力.
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