作为抗癌治疗结果的指纹变化:一个系统的综合性审查
Silvia Belloni1, Arianna Magon2, Rita de Sanctis3
1Department of Public Health, Experimental and Forensic Medicine, Section of Hygiene, University of Pavia, Pavia, Italy.
Seminars in oncology
|March 4, 2025
概括
某些癌症治疗方法,如capecitabine和taxane,可以改变成年癌症患者的指纹. 需要更多的研究来了解这些抗癌治疗对指纹模式的全部影响.
科学领域:
- 在瘤学瘤学.
- 法医科学 法医科学 法医科学
- 皮肤病学 皮肤病学
背景情况:
- 指纹识别在法医中至关重要.
- 癌症治疗对指纹的影响在很大程度上是未知的.
- 抗癌疗法可能会影响皮肤特征.
研究的目的:
- 审查证据,将癌症治疗与成年人的指纹改变联系起来.
- 分析这种现象在癌症患者中的程度.
主要方法:
- 按照PRISMA和Cochrane指南进行系统整合性审查.
- 在PubMed,CINAHL,科学网,Scopus (2024年8月至11月) 中进行了搜索.
- 评估了包含的研究的方法质量.
主要成果:
- 包括5个实验研究和9个案例报告来自176个记录.
- 发现了capecitabine,taxan,氨酸激酶抑制剂和指纹变化之间的相关性.
- 在患有乳腺癌和结直肠癌的患者中观察到;研究大多是中度到低质量的.
结论:
- 指纹变化是特定抗癌治疗的记录后果.
- 需要更大,更精心设计的研究来量化负担和具体方案.
- 进一步的研究应侧重于特定人群和治疗方案.
相关概念视频
Cancer Prevention
6.0K
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Some...
6.0K
Cancer Therapies
7.5K
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
7.5K
Targeted Cancer Therapies
7.4K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
There are several types of targeted therapies against...
7.4K
Treatment Resistant Cancers
3.2K
Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
3.2K
Combination Therapies and Personalized Medicine
4.8K
Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
4.8K


